Prion variants, species barriers, generation and propagation
نویسندگان
چکیده
Prion variants faithfully propagate across species barriers, but if the barrier is too high, new variants (mutants) are selected, as shown in a recent BMC Biology report. Protein sequence alteration can prevent accurate structural templating at filament ends producing prion variants.
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ورودعنوان ژورنال:
- Journal of Biology
دوره 8 شماره
صفحات -
تاریخ انتشار 2009